Cataract Pathogenesis: Results of Epidemiological Studies and Experimental Models

Cataract "93, 4th International Cataract Epidemiology Meeting Me (Developments in Ophthalmology)
  • 100 Pages
  • 1.39 MB
  • 4154 Downloads
  • English
by
S. Karger AG (Switzerland)
Epidemiology & medical statistics, Ophthalmology, Medical / Nursing, Health/Fi
ContributionsK. Sasaki (Editor)
The Physical Object
FormatHardcover
ID Numbers
Open LibraryOL12930405M
ISBN 103805559879
ISBN 139783805559874

Cataract Pathogenesis: Results of Epidemiological Studies and Experimental Models: Cataract '93, 4th International Cataract Epidemiology Meeting Me (Developments in Ophthalmology, Vol. 26) [Hockwin, O., Sasaki, K., Bandello, F.] on *FREE* shipping on qualifying offers. Cataract Pathogenesis: Results of Epidemiological Studies and Experimental Models: Cataract '93, 4th Price: $ A Population-Based Estimate of Cataract Prevalence: The Melbourne Visual Impairment Project Experience / P.M.

Livingston, C.S. Guest, Y. Stanislavsky, S. Lee, S.

Details Cataract Pathogenesis: Results of Epidemiological Studies and Experimental Models PDF

Bayley, C. Walker, C. McKean and H.R. Taylor --Selection of Populations and Samples in the Design of Epidemiological Studies of Cataract / C.S. Guest --Diabetes, Sex, and Cataract / J.

Author(s): Hockwin,Otto; Sasaki,K(Kazuyuki),; International Cataract Epidemiology Meeting,(4th: Melbourne, Vic.) Title(s): Cataract pathogenesis. Reviewed by: L Stephen Kwok PhD Department of Optometry The University of Auckland NEW ZEALAND Clinical and Experimental Optometry July-August Book reviews Cataract Pathogenesis: Results of Epidemiological Studies and Experimental Models 0 Hockwin and K Sasaki, eds.

Switzerland: Karger pages RRP A$ This rather small book. These models have been used to either study the cataract pathogenesis or to trial anticataract therapies with the long-term view to reduce the incidence of cataract in humans.

While one experimental system cannot entirely replicate the cataract process in humans, investigators need to be mindful of selecting an appropriate animal : Julie C. Lim, Irene Vorontsova, Renita M. Martis, Paul J. Donaldson. words of a volume entitled Cataract Pathogenesis, contammg papers presented to the 4th International Cataract Epidemiology Meeting, 1 The number of Americans reported to be suffering from cataract in was millions, an estimate based on the United States Health Interview.

PDF | The effect of a novel flavonoid, venoruton (a mixture of mono- di- tri- and tetrahydroxyethylrutosides) has been investigated in healthy rat |. Lens and cataract research from a clinical, biophysical, biological and mainly biochemical point of view has a long tradition. Already since the beginning of the 20th century research relating to.

On the basis of epidemiological studies of myopia, experimental animal models of myopia, and analysis of people with visual deprivation early in life, a model of myopia development can be postulated (fig (fig4). Prolonged near work was thought to lead to progressive myopia through the direct physical effect of prolonged accumulation, but.

Recent experimental data issued from retinal cell cultures and eye disease animal study models demonstrated the protective effects of resveratrol toward eye disorders. A large number of studies have demonstrated that resveratrol is able to act as an antioxidant, as an Cataract Pathogenesis: Results of Epidemiological Studies and Experimental Models book agent or as a sirtuin activator in the eye.

A large body of work on animal models (such as chicks, guinea pigs, and monkeys) has been instrumental to our understanding of visually guided ocular growth, and potential mechanisms leading to myopia. These studies have shown that experimentally degrading the quality of the image formed on the retina by introducing translucent diffusers (i.e Author: Ranjay Chakraborty, Scott A.

Read, Stephen J. Vincent. The necessity to standardize cataract evaluation systems for epidemiological studies ICRP [ ] defined the threshold as the dose that causes a particular effect in 1% of exposed individuals. With the approach of ICRP [ 81 ], the population size required to detect a 1% risk with statistical significance was estimated to be ∼46 people Cited by:   A number of studies of human glaucoma and in vitro and in vivo experimental models have used proteomics analysis techniques.

Distinct proteomics techniques have been applied to analyze diverse sample types, including optic nerve, retina, sclera, trabecular meshwork, aqueous humor, pseudoexfoliative material, tear, and blood. Studies to determine the cataract-impeding effects of a number of molecules have produced less than definitive results in the human field, principally because it is difficult to confine a human subject to a specific dietary regime.

Epidemiological studies have sought to correlate degree of cataract with dietary inputs in humans with limited. Washington, DC: The National Academies Press.

doi: / one would still have to deter- mine whether VDT use actually caused the cataract.) In principle, experimental studies on animals or epidemiological studies or both could be used. In an experimental study, monkeys (whose lenses have radiosensitivity similar to that of humans.

The necessity to standardize cataract evaluation systems for epidemiological studies ICRP [ 2 ] defined the threshold as the dose that causes a particular effect in 1% of exposed individuals.

With the approach of ICRP [ 81 ], the population size required to detect a 1% risk with statistical significance was estimated to be ~46 people.

A year-old man with age-related macular degeneration noted a gradual decrease in vision in his left eye. He had undergone indocyanine green enhanced diode laser photocoagulation 15 months earlier for choroidal neovascularization- On examination, his visual acuity in this eye was 20 Slit-lamp biomicroscopy (A) revealed an atrophic chorioretinal scar superonasal to the fovea and a /5.

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Oxidative stress and the subsequent oxidative damage to lens proteins is a known causative factor in the initiation and progression of cataract formation, the leading cause of blindness in the world today. Due to the role of oxidative damage in the etiology of cataract, antioxidants have been prompted as therapeutic options to delay and/or prevent disease by: 2.

Purpose. Acanthamoeba keratitis is a severe, often sight threatening, corneal infection which in Western countries is predominantly seen in daily wear of contact lenses. This review aims to summarise the pathobiology and epidemiology of contact lens‐related Acanthamoeba keratitis, and to present strategies for prevention, particularly with respect to modifiable risk factors in contact lens by:   MANY epidemiological studies 1,2 have revealed that cigarette smoking is a strong risk factor for cataract development in both men and women.

The most probable mechanism by which cigarette smoke contributes to cataractogenesis is oxidative damage 3,4 because cigarette smoke–exposed tissues contain large amounts of reactive oxygen species (ROS) and by: International Journal of Ophthalmology and Clinical Research is an international open access, peer reviewed journal for visual science specialist and ophthalmologists.

IJOCR serves the research field by publishing original articles in clinical and basic science research and other articles relating to the sense of sight.

Excellence in IJOCR is attained through unbiased peer review, elevated. The purpose of this meta-analysis was to evaluate the relationship between blood lutein and zeaxanthin concentration and the risk of age-related cataract (ARC).

MEDLINE, EMBASE, ISI and Cochrane Library were searched to identify relevant studies up to April Meta-analysis was conducted to obtain pooled relative risks (RRs) for the highest-versus-lowest categories of blood lutein and Cited by: 10 Metabolic and Cardiovascular Disorders.

Chapter Overview. Based on new evidence and a review of prior studies, the current committee found that new scientific evidence combined with previously reviewed studies has led to changes in the categorizations of association for two metabolic and cardiovascular outcomes outcomes: type 2 diabetes and hypertension.

Ibuprofen has become one of the foremost pain-relieving medications world-wide with its proven safety and efficacy in a wide variety of painful and inflammatory conditions. It has also been widely investigated for application in a variety of painful and non-pain inflammatory states including cancer and neurodegenerative conditions, reflecting the unique and novel properties of the drug that.

Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and one of the major causes of blindness worldwide. The pathogenesis of DR has been investigated using several animal models of diabetes.

These models have been generated by pharmacological induction, feeding a galactose diet, and spontaneously by selective inbreeding or genetic by:   The NOOK Book (eBook) of the Ibuprofen: Discovery, Development and Therapeutics by K. Rainsford at Barnes & Noble. FREE Shipping on Pages: Epidemiological studies strongly suggest that excessive adiposity, decreased physical activity, and unhealthy diets are key players in the pathogenesis and prognosis of many common cancers.

In addition, calorie restriction (CR), without malnutrition, has been shown to be broadly effective in cancer prevention in laboratory strains of rodents. Studies of animal models of some of these diseases confirm the potential for an effect of UV-B on the development of infectious disease processes [Howie, a,b; Giannini, ; Taylor, ].

Figure presents a model of how ultraviolet radiation is thought to interact with skin inducing Ts cells resulting in specific non-responsiveness to. Intermediate uveitis has been reported in –22 % of uveitis patients and there are limited data on the incidence of pars planitis (Chan et al.

; Foster and Vitale ; Henderly et al.

Description Cataract Pathogenesis: Results of Epidemiological Studies and Experimental Models FB2

; McCannel et al. ; Rodriguez et al. ).The rate of perper year was reported by The Northern California Epidemiology of Uveitis Study (Gritz and Wong ).Cited by: 4. Virology is currently one of the most dynamic and rapidly changing fields of clinical medicine.

The new third edition of this essential reference has been extensively revised and updated to incorporate the latest developments and relevant research. Covering novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, Clinical Virology informs scientists and health care.

This literature review summarizes current knowledge of the role of HDL-C, if any, in pathogenesis and progression of four age-related ocular diseases, namely age-related macular degeneration (AMD), age-related cataract, glaucoma, and diabetic retinopathy (DR), and will primarily discuss epidemiological and genetic evidence.This book covers several interesting topics such as why normal tension glaucoma (NTG) patients still develops into glaucoma without high intraocular pressure (IOP); and whether there are factors other than IOP contributing to the pathogenesis of NTG why the role of IOP in the pathogenesis of POAG becomes vague and controversial.The Cataract PORT reviewed the incidence of cataract complications from studies published prior to and with an overall phacoemulsification/manual ECCE case mix of Six subsequent studies of adverse perioperative outcomes from cataract surgery are.